Benzoic acid, 3-amino-2-bromo-, methyl ester

Benzoic acid, 3-amino-2-bromo-, methyl ester - Names and Identifiers

Name	3-Amino-2-bromo-benzoic acid methyl ester
Synonyms	Methyl 3-aMino-2-broMobenzoate methyl 3-amino-2-bromobenzoate Methyl 3-amino-2-bromobenzoate 3-Amino-2-bromo-benzoicacidmethylester 3-AMINO-2-BROMO-BENZOIC ACID METHYL ESTER 3-Amino-2-bromo-benzoic acid methyl ester Benzoic acid, 3-amino-2-bromo-, methyl ester benzoic acid, 3-amino-2-bromo-, methyl ester
CAS	106896-48-4
InChI	InChI=1/C8H8BrNO2/c1-12-8(11)5-3-2-4-6(10)7(5)9/h2-4H,10H2,1H3

Benzoic acid, 3-amino-2-bromo-, methyl ester - Physico-chemical Properties

Molecular Formula	C8H8BrNO2
Molar Mass	230.06
Density	1.583 g/mL at 25 °C
Boling Point	314.133°C at 760 mmHg
Flash Point	>110℃
Vapor Presure	0mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	n20/D1.601

Benzoic acid, 3-amino-2-bromo-, methyl ester - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
UN IDs	2810
WGK Germany	3
Hazard Class	6.1
Packing Group	Ⅲ

Benzoic acid, 3-amino-2-bromo-, methyl ester - Introduction

3-amino -2-bromo benzoic acid methyl ester, chemical formula is C8H8BrNO2, its nature, use, preparation method and safety information are as follows:

Nature:
1. Appearance: 3-amino -2-bromo benzoic acid methyl ester is a white solid or crystalline powder.
2. Solubility: It can be dissolved in organic solvents such as ethanol, ether and chloroform, and is not easy to dissolve in water.
3. Melting point: Its melting point is about 100-102 degrees Celsius.
4. chemical properties: the compound is a sulfonating agent, can participate in electrophilic substitution reaction.

Use:
1. 3-amino -2-bromo benzoic acid methyl ester can be used in the synthesis of pharmaceutical and pesticide intermediates, such as for the synthesis of certain drugs and pesticides.
2. It can also be used as a substrate in organic synthesis to construct structures containing amino and bromine groups.

Preparation Method:
3-Amino-2-bromobenzoic acid methyl ester can be synthesized by the following steps:
1.3-amino -2-bromo benzoic acid is reacted with methanol to generate 3-amino -2-bromo benzoic acid methyl ester.

Safety Information:
1. 3-Amino-2-bromobenzoic acid methyl ester may cause irritation to the skin, eyes and respiratory tract when suspended and dissolved, so appropriate protective equipment should be worn during operation.
2. Avoid contact with oxidants and strong acids to prevent dangerous chemical reactions.
3. in storage and handling to avoid high temperature and fire.

Please note that when synthesizing and using this compound in the laboratory, relevant safety procedures must be followed and appropriate laboratory precautions must be taken.

Last Update：2024-04-09 20:49:11